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[0043] In certain embodiments, a pharmaceutical composition for oral administration comprises (i) about 1 mg to about 10 mg of a bislipidated GLP-1 peptide analog

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Afferent fibers from the trigeminal ganglion synapse on neurons in the trigeminal cervical complex (2), and ascending pathways transmit signals to various brain regions, causing pain, cutaneous allodynia, and sensory disturbances like photophobia and phonophobia (6, 34)